Sustained Delivery of Chondroitinase ABC from Hydrogel System
نویسندگان
چکیده
منابع مشابه
Sustained Delivery of Chondroitinase ABC from Hydrogel System
In the injured spinal cord, chondroitin sulfate proteoglycans (CSPGs) are the principal responsible of axon growth inhibition and they contribute to regenerative failure, promoting glial scar formation. Chondroitinase ABC (chABC) is known for being able to digest proteoglycans, thus degrading glial scar and favoring axonal regrowth. However, its classic administration is invasive, infection-pro...
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ژورنال
عنوان ژورنال: Journal of Functional Biomaterials
سال: 2012
ISSN: 2079-4983
DOI: 10.3390/jfb3010199